1. Introduction

The present study was aimed at evaluating the efficacy and safety of quetiapine (Seroquel) in the treatment of borderline personality disorder in adults [

].

Quetiapine is a synthetic drug commonly used in the management of schizophrenia [

It is a selective serotonin reuptake inhibitor (SSRI) that acts on the serotonergic neurotransmission mechanism by increasing serotonin levels in the brain [

In clinical practice, it is often used as an adjunctive treatment to augment treatment with dopamine agonists [

The clinical practice is to prescribe this drug at a dosage of 25–30 mg daily and to gradually reduce the dosage over time [

In addition, the clinical practice has been to consider the efficacy and safety of this treatment in patients with borderline personality disorder (BPD) [

In the current study, we investigated the efficacy and safety of quetiapine in the treatment of BPD in adults. This study aimed to evaluate the efficacy and safety of quetiapine in the treatment of patients with BPD and their partners with borderline personality disorder.

2. Materials and Methods

This was a retrospective analysis of the medical records of all patients who met the following criteria:

1. Primary BPD, defined as having a diagnosis of BPD or of a diagnosis of borderline personality disorder
2. Primary BPD without borderline personality disorder, defined as being male
3. Primary BPD with borderline personality disorder, defined as having a diagnosis of BPD or of a diagnosis of BPD, including psychosis, depression, or psychotic disorder
4. Primary BPD with psychosis, depression, or psychotic disorder, defined as having a diagnosis of psychosis
5. BPD with psychosis, depression, or psychotic disorder, defined as having a diagnosis of BPD or a diagnosis of BPD
6. Primary BPD, defined as having a diagnosis of BPD or a diagnosis of BPD, with or without borderline personality disorder
7. Primary BPD without psychosis, depression, or psychotic disorder, defined as having a diagnosis of psychosis

A total of 832 patients with primary BPD were included in the study, of which 295 (58.2%) were males and 597 (51.8%) were females, with mean age of 32 years, age range 18–70 years. Patients with a mean age of 64 years had a mean duration of BPD of 14.6 months. The diagnosis of BPD was made based on the following criteria:

1. BPH or a family history of BPH
2. History of psychosis, depression, or psychotic disorder
3. Primary BPH
4. BPH with a history of psychosis, depression, or psychotic disorder
5. BPH with a history of depression or psychosis
6. BPH with a history of psychosis
7. BPH with a history of depression

Patients with BPD were divided into four groups:

1. Primary BPD
2. Patients with a diagnosis of BPD
3. Patients with a diagnosis of BPD with a history of psychosis, depression, or psychotic disorder

3. Results

In the BPD group, the mean age of the patients was significantly lower than that of the other two groups (

<0.001). In the BPD with borderline personality disorder group, the mean age was significantly lower than that of the other two groups (

The mean duration of treatment was 12.8 months. The mean total dosage was significantly lower in the BPD group than in the BPD with psychosis (

The mean total duration of treatment was 8.3 months in the BPD with borderline personality disorder group and 5.

1. Why is Seroquel prescribed?

Seroquel (quetiapine fumarate) is a type of prescription medication called a‘‘.’A doctor will prescribe Seroquel for a specific condition or patient based on factors such as age, weight, medical history, laboratory tests, and ultrasound findings. Your doctor will likely prescribe this medication for another reason.

2. What should I know before I take Seroquel?

Do not take Seroquel if you have an allergy to quetiapine fumarate or any of the ingredients in this medicine.

Before taking Seroquel, tell your doctor about all your medical conditions, including if you:

• have liver disease, high cholesterol, triglycerides in your blood, high blood pressure, diabetes, heart disease, or heart failure, have a seizure or serious muscle problems (for example, multiple myeloma or leukaemia).
• have a history of blood clotting disorders, such as protein-bound or myoglobinuria.
• have any allergies to quetiapine fumarate, quetiapine fumarate, or any other ingredients in this medicine.
• seizure or seizure disorders, such as cerebral palsy, multiple sclerosis, Parkinson's disease, or spinal cord diseases.

3. Can I take Seroquel if I am pregnant or breastfeeding?

No, you should not take Seroquel if you are pregnant or breastfeeding.

The maximum daily dose is one dose per day.

4. What should I know while taking Seroquel?

Things you should do	Things you should avoid
Practice safe sex Avoid sexual intercourse Do not use if you have ever had an allergic reaction to quetiapine fumarate, quetiapine fumarate, or any other ingredient in Seroquel.

By understanding and using Seroquel as directed, patients can safely and effectively manage their condition. If you have questions or concerns, please feel free to ask. For more information, see.

5. Are there any side effects?

Allergic reactions are not a reason to stop taking Seroquel. However, there have been reports of side effects such as:

• Feeling faint or dizzy
• Feeling sick
• Diarrhea
• Increased urination
• Nausea

These side effects are usually mild and temporary. If you experience an allergic reaction, stop taking Seroquel and see a doctor immediately.

6. How should I take Seroquel?

Take this medicine in the dose and duration as directed by your doctor. Depending on your condition, your doctor may adjust your dosage or monitor you for side effects.

Follow the directions for the medicine on your prescription label and ask your doctor or pharmacist if you have any questions.

The usual recommended dose of Seroquel is one tablet once a day, but your doctor may increase your dose to two tablets once a day.

There are several other strengths and forms of Seroquel available.

Disclaimer:

Please note that this medication information is not medical advice and should not replace the advice of your doctor or other medical professional.

Read More Is Seroquel Safe for Older People?

Quetiapine fumarate is a prescription medicine used to treat certain mental and physical conditions. It is not intended for use by women or children.

Seroquel is best taken with food, especially if you have a history of kidney problems or liver problems. Do not take this medicine with food that is affected by kidney problems.

How to Use Seroquel Quetiapine

Using Seroquel Quetiapine is easy to do. Simply take this medication by mouth as directed on the prescription label, usually once or twice daily, once a day. Your doctor may recommend daily use for several weeks if you finish this dose and your symptoms improve.

Dosage and Administration

When using Seroquel Quetiapine, follow these instructions:

1. Read the Medication Guide provided by your pharmacist before you start using Seroquel Quetiapine and each time you get a refill.
2. If you miss a dose of Seroquel Quetiapine, take it as soon as possible. If it is almost time for the next dose, skip the one that will be missed.
3. The first dose should be taken at the same time each day. Do not take a double dose to make up for a missed dose.

Contraindications

Using Seroquel Quetiapine may be contraindicated in certain situations. For example, if you have a known hypersensitivity to quetiapine or any other ingredient of this medication.

If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor before taking Seroquel Quetiapine. Seroquel Quetiapine should not be used during pregnancy or during breastfeeding.

Inform your doctor if you have liver disease, depression, bipolar disorder, nerve pain, seizures, or any other mood disorder, or if you have liver or kidney disease.

Side Effects

Using Seroquel Quetiapine may cause some side effects. If you experience any of these serious side effects, stop taking Seroquel Quetiapine and call your doctor immediately or seek immediate medical attention.

Precautions

Use of this medication may not be safe for people who are pregnant or may become pregnant.

1. Tell your doctor about all your medical conditions, including if you have diabetes, asthma, or had a stroke or heart attack.
2. Use caution if you have low blood pressure, taking certain medications, or if you have liver disease.
3. Be aware that Seroquel Quetiapine can cause a serious increase in your heart rate. Your doctor will need to monitor your heart rate for the best outcome.
4. Use caution if you have a seizure disorder or have a condition called major depression. This medication may cause a serious increase in your heart rate.
5. Tell your doctor about all the medications you are taking, especially nitrates, cimetidine, and protease inhibitors. Seroquel Quetiapine may make you dizzy or drowsy.
6. Seroquel Quetiapine may affect how other medications work or may make your skin more sensitive to sunlight.

Before taking Seroquel Quetiapine, tell your doctor about all the medications you are taking, especially antifungals, antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Inform your doctor of all medicines and medical devices (including prescription and nonprescription medicine) before using Seroquel Quetiapine.

Possible Side Effects

Seroquel Quetiapine can cause side effects. Tell your doctor about all the side effects that you have. Your doctor may need to change the doses of your medications or monitor you carefully for them.

Seroquel Quetiapine may cause a drowsiness when standing up. Do not drive a car or operate machinery. Avoid activities requiring mental alertness or alertness products (e.g., walking, bending over, or sitting up oreuropean lispro).

Seroquel Quetiapine may cause a seizure. Seizures usually last between six and twelve hours.

The seizure frequency can vary depending on the severity and location of the side effects. Stop using Seroquel Quetiapine and call your doctor right away if you have any of these serious side effects.

The most serious side effects of Seroquel Quetiapine include a life-threatening allergic reaction.

Aquariel (Seroquel) - 20 mg per tablet

What is this medicine? This medicine is used to treat schizophrenia, bipolar disorder, and major depressive disorder in adults and adolescents. This medicine may be used for other purposes

How to use This medicine? It is swallowed whole with a glass of water. This medicine can be taken on an empty stomach or with food. If stomach upset occurs, take the medicine with food. Follow the directions on your prescription label.

What should I tell my health care professional before using this medicine? Your health care professional will want to know about any previous history of heart disease, stroke, high or low blood pressure, or gastrointestinal problems. Your health care professional will also need to know if you are pregnant or breast-feeding.

Before taking this medicine, tell your health care professional about all of your health problems, especially if you:

• are taking or have taken certain medicines
• are taking other medicines, including over the counter medicines and herbal supplements, that contain sertraline, a medicine used to treat depression
• have a family history of diabetes or high blood pressure
• are taking the antipsychotic medication pimozide, a medicine used to treat schizophrenia
• have heart problems such as heart failure, irregular heartbeat, and heart attack
• are taking certain other medicines, including herbal medicines, over the counter medicines and other medicines that may help to treat depression.

This medicine may not be safe for use while you are pregnant or breast-feeding. Talk to your health care professional before taking this medicine during pregnancy or if you are breast-feeding.

How should I take this medicine?

The recommended dose for adults and adolescents aged 12 and above is 50 mg once a day, divided into 2 or 3 equal parts. Your doctor will determine the correct dose for you.

Take this medicine with a full glass of water. Do not take your medicine with any other food, except on a doctor's advice.

The dose may be increased or decreased as needed.

Follow all directions on your prescription label and read all medication guides or instruction sheets carefully. If you are taking any type of medicine, including this medicine, ask your health care professional to review your prescription and take this medicine only if your doctor has judged that the benefit to you is greater than the risk of side effects. This medicine may cause mild stomach pain, nausea, diarrhea, constipation, flatulence, heartburn, headache, dizziness, drowsiness, muscle aches, itching, tiredness, weight gain, weakness, numbness, or weakness. If symptoms last more than 4 hours, stop using this medicine and contact your health care professional immediately.

The following are some common side effects of this medicine: nausea, dry mouth, constipation, stomach pain, loss of appetite, blurred vision, increased appetite, light sensitivity, dry mouth, constipation, headache, dizziness, drowsiness, fatigue, dizziness, weakness, tiredness, sleep disturbance, stomach cramps, nausea, vomiting, and stomach pain.

This medicine may cause serious side effects including: hallucinations, fever, swollen lymph nodes, muscle pain, or sore throat.

Tell your health care professional about all the medicines you take, including prescription and OTC medicines, over-the-counter medicines, herbal medicines, and vitamins, as they may interact with this medicine. Especially tell your health care professional if you take any of the following:

• antacids, such as sucralfate (St.